The Codex Claromontanus manuscript is found as a vellum (or wool parchment) recording of Paul's epistles and the Book of Hebrews in Greek and Latin on facing pages.

Dionysius Exiguus establishes "Anno Domini" as a dating system (AD) under Julian and Gregorian calendars.

Justinian closes the Academy of Athens (originally formed by Plato in 387 BC).

The Chinese develop block book printing for carving proof texts into wood.

Cassiodorus, a Roman statesman, founds a monastery and establishes a scriptorium for the copying and preserving of secular works of literature.

Mohammed is born in Mecca.

The Synod of Toledo inserts a filioque to the Nicene Creed stating that the Holy Spirit proceeds from the Father and the Son. This statement is later officially adopted by Rome.